Isolation of temperature-sensitive mutants of murine sarcoma virus.

نویسندگان

  • E M Scolnick
  • J R Stephenson
  • S A Aaronson
چکیده

Three separate murine sarcoma virus nonproducer cell lines have been isolated which are temperature sensitive for the maintenance of transformation. In each case, a viral rather than a cellular genetic mutation is the reason for the temperature-sensitive effect. Superinfection of one of the mutants with murine leukemia virus overcomes the temperature-sensitive change in the transformed state.

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عنوان ژورنال:
  • Journal of virology

دوره 10 4  شماره 

صفحات  -

تاریخ انتشار 1972